Using OPM's platform fed-batch cell culture process that is not optimized for specific antibodies or recombinant proteins, the average expression level of accomplished client projects has reached above 4.4 g/L. Sample shown in the graph include monoclonal antibodies, bispecific antibodies and fusion proteins. During single clone selection processes, quality attributes are gradually taken into consideration to ensure that selected clones meet both productivity and quality requirements.

Vector design for bispecific antibodies - Optimal theoretical combination obtained through proportional design of gene cassettes and adjustment of key elements
Transfection design - Optimal peptide chain ratio achieved by considering different transcription & translation efficiency of different elements
Expanded selection range - based on structural characteristics, selection range can be expanded to obtain better clones