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Home   >   Products   >   CHO Cell Culture Media  >   StarCHO Feed Plus Medium

StarCHO™ Feed Plus Medium

StarCHO Feed Plus-1

StarCHO Feed Plus is a chemically defined feed medium formulated for high-density fed-batch processes across multiple Chinese hamster ovary (CHO) cell subtypes. It is hydrolysate-free, animal-origin free (AOF), and does not contain L-glutamine. It contains 83 g/L D-glucose.

Recommended cell subtypes: CHOZN GS-/-, etc. 

Recommended companion media: StarCHO™, StarCHO™ Plus, and CDFS12™ Feed Supplement

This product is intended for research use or further manufacturing, including large-scale biopharmaceutical production. It is not intended for direct human administration or use as a drug substance or drug product.

Product Highlights

  • Delivers high yields across different CHO cell lines while maintaining high cell densities and viability for robust bioprocessing

  • GMP-ready for seamless R&D-to-GMP transition

  • Robust intra- and inter-lot consistency (RSD <5%)

  • Flexible packaging formats (dry powder media or liquid)
Titer Comparison for StarCHO Plus and StarCHO Feed Plus-1

StarCHO Feed Plus, used in combination with StarCHO Plus Medium and CDFS12 Feed Supplement, outperformed a competitor in CHOZN GS-/-mAb expression, showing 90% titer increase on Day 14, with higher late-stage VCDs and viability. 

Note: Representative fed-batch example. Refer to our Selection Guide or contact OPM Support for cell line-specific recommendations.

VCD Comparison for StarCHO Plus and StarCHO Feed Plus-1

StarCHO Feed Plus, used in combination with StarCHO Plus Medium and CDFS12 Feed Supplement, outperformed a competitor in CHOZN GS-/-mAb expression, showing 90% titer increase on Day 14, with higher late-stage VCDs and viability. 

Note: Representative fed-batch example. Refer to our Selection Guide or contact OPM Support for cell line-specific recommendations.

  • StarCHO Feed Plus Product Insert  Download Now >
  • SDS - coming soon
  • See Certificates of Analysis (CoAs) - coming soon

Guide and Flyers

Poster

  • Empowering CHOZN® GS-/- Cells: Advanced Media & Feed Optimization for Sustained Viability and Exceptional mAb Titers in Extended Fed-Batch Processes  View Now >

FAQ

Is this medium intended for batch, fed-batch, or perfusion culture?

Our basal media and corresponding feed supplements are formulated for flexible use across various culture modes, including batch, fed-batch, and perfusion systems. We recommend using our dedicated feed protocols to achieve the most stable and optimal fed-batch performance. 

Which major CHO host cell lines are compatible with your media?

Our platform media is optimized for high-density growth and robust expression across various CHO host cell lines, including but not limited to CHO-K1, CHO-S, DG44, and GS-CHO systems. If you have a highly engineered cell line, we encourage you to submit an inquiry so our technical experts can properly assess. 

Do you offer media customization?

Yes! Customization is one of OPM's core strengths. Our media platform allows us to provide rapid and flexible formulation adjustments and optimization based on your specific cell line, desired yield, and process requirements. Our expert team is available to help screen for the optimal media formulation in a shortened timeline. Contact us to get your personalized consultation.

Related Products

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StarCHO

High-performance basal medium compatible with StarCHO Feed Plus

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StarCHO Plus

High-performance basal medium compatible with StarCHO Feed Plus

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CDFS12

Feed supplement compatible with StarCHO Feed Plus

Simple.

Easily select CHO media and feeds that are proven to work specifically with your CHO-K1, CHO-DG44, CHO-S, or CHOZN cell line.

Fast.

Order your cell culture media samples / products by contacting us and get it delivered directly to you in less than 2 weeks.

Reliable.

Questions? Connect with one of our cell culture specialists to help you get to your next milestone, faster. Online resources available 24/7.