Our mission is to optimize cell culture so life-saving biologics reach patients faster and more affordably.

OPM was founded in 2013 by Dr. Zhihua Xiao to make cell culture media a lever for lower costs and better quality.

Optimization became the principle behind everything we build, and it gave us our name: OPM comes from the word optimization.

Today we make chemically defined, animal-origin-free media for CHO, HEK293, and other cells, and develop custom media for programs that need more. Customers who switch see an average 96% higher titer and 35%+ lower costs.

We manufacture media at two GMP sites, in batches of up to 2,000 kg dry powder and 2,000 L liquid media. With two sites, a backup is always ready, so your supply holds even when the unexpected happens.

Through our CRDMO arms, Sureness and PharmaLegacy, we also run discovery, development, and manufacturing services, so media scientists and process engineers work on the same program from the start. 

Our teams are spread across the Bay Area, San Diego, Boston, New York, France, and China, ready to serve biotech communities worldwide.

OPM by the numbers