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Home > Products > CHO Cell Culture Media > StarCHO Medium
StarCHO™ Medium

StarCHO is a chemically defined basal medium formulated for thawing, passaging, and supporting high-density fed-batch processes across multiple Chinese hamster ovary (CHO) cell subtypes. It is hydrolysate-free, animal-origin free (AOF), and does not contain L-glutamine. It contains 6 g/L D-glucose.
Recommended cell subtypes: CHOZN GS-/-.
Recommended companion media: StarCHO™ Feed Plus and CDFS12™ Feed Supplement.
This product is intended for research use or further manufacturing, including large-scale biopharmaceutical production. It is not intended for direct human administration or use as a drug substance or drug product.
Product Highlights
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Delivers high yields across different CHO cell lines while maintaining high cell densities and viability for robust bioprocessing
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GMP-ready for seamless R&D-to-GMP transition
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Robust intra- and inter-lot consistency (RSD <5%)
- Flexible packaging formats (dry powder media or liquid)
StarCHO Medium, when fed StarCHO Feed and CDFS36 Feed Supplement, outperformed a competitor in CHOZN GS-/- mAb expression, showing 130% titer increase on day 14, with higher late-stage VCDs and comparable viability.
Note: Representative fed-batch example. Refer to our Selection Guide or contact OPM Support for cell line-specific recommendations.
StarCHO Medium, when fed StarCHO Feed and CDFS36 Feed Supplement, outperformed a competitor in CHOZN GS-/- mAb expression, showing 130% titer increase on day 14, with higher late-stage VCDs and comparable viability.
Note: Representative fed-batch example. Refer to our Selection Guide or contact OPM Support for cell line-specific recommendations.
- StarCHO Product Insert Download Now >
- SDS - coming soon
- See Certificates of Analysis (CoAs) - coming soon
Guide and Flyers
- CHO Cell Media & Feed Selection Guide Download Now >
- Maximize Your Protein Production with OPM-CHO Platform Download Now >
Poster
- Empowering CHOZN® GS-/- Cells: Advanced Media & Feed Optimization for Sustained Viability and Exceptional mAb Titers in Extended Fed-Batch Processes View Now >
FAQ
Is this medium intended for batch, fed-batch, or perfusion culture?
Our basal media and corresponding feed supplements are formulated for flexible use across various culture modes, including batch, fed-batch, and perfusion systems. We recommend using our dedicated feed protocols to achieve the most stable and optimal fed-batch performance.
Which major CHO host cell lines are compatible with your media?
Our platform media is optimized for high-density growth and robust expression across various CHO host cell lines, including but not limited to CHO-K1, CHO-S, DG44, and GS-CHO systems. If you have a highly engineered cell line, we encourage you to submit an inquiry so our technical experts can properly assess.
Do you offer media customization?
Yes! Customization is one of OPM's core strengths. Our media platform allows us to provide rapid and flexible formulation adjustments and optimization based on your specific cell line, desired yield, and process requirements. Our expert team is available to help screen for the optimal media formulation in a shortened timeline. Contact us to get your personalized consultation.
Related Products
StarCHO Feed Plus
High-performance feed medium compatible with StarCHO
CDFS12 Feed Supplement
Feed supplement compatible with StarCHO